Kolkata: Skyrocketing prices of cattle did not deter people from buying goats and dumbas (Arabian Lamb) on the eve of Bakrid, to be observed on Monday.A goat weighing around 30 kg drew the attention of customers at the Zakariya Street goat market this year. “On Saturday, I sold a goat for Rs 1.10 lakh. The person who bought it lives near Moulali. I have only one goat left with me. Its name is Praveer and its two-years-old,” said Shubham Sharma, the seller of the goat. Also Read – Bengal family worships Muslim girl as Goddess Durga in Kumari PujaEvery day, the goat maintains a special diet consisting of grams and banana leaves among others, amounting to a total cost of around Rs 200 per day. While the price of small goats starts at Rs 8,500, the cost of medium sized goats varies between Rs 12,000 and Rs 15,000. The Narkeldanga and Kidderpore cattle markets are usually preferred by people buying average sized goats, while the market near Nakhoda Masjid is known for high priced goats and dumbas. “I had brought 12 dumbas. I have already sold eight of them and by tonight, all the dumbas will be sold out,” said Kalim, a goat and dumba seller. Bakrid, also known as Eid al-Adha, is the festival of sacrifice celebrated in the honour of prophet Ibrahim, the messenger in Islam who was willing to sacrifice his son as an act of respect towards God’s command.
SONY Pictures Entertainment, ABC’s The Good Doctor, Netflix’s Atypical, and several filmmakers were honored for their contributions to autism awareness “From Spectrum to Screen” by the Autism Society of America at the 2nd Annual AutFest International Film Festival (April 28-29), held at the Writers Guild Theater in Beverly Hills.Ed Asner at 2nd Annual AutFest Film FestivalCredit/Copyright: Mathew ImagingAutFest screened over 16 feature films, shorts and television programs that promote autism awareness and/or are made by autistic filmmakers.Seven-time Emmy winner and autism advocate Ed Asner presented SONY Pictures Entertainment with the AutFest Visionary Award, bestowed upon Jeff Frost, President of Sony Pictures Television Studios, and Co-Presidents of Sony Pictures Television Chris Parnell and Jason Clodfelter at the festival’s closing reception. ABC’s The Good Doctor and Netflix’s Atypical received Spotlight Awards, honored for their exceptional portrayal of autism in a positive light to help increase understanding and acceptance of people on the spectrum.Prior to the reception, cast and crew of Netflix’s Atypical participated in a Q&A moderated by PEOPLE reporter Kara Warner after a screening of two episodes. Participating in the panel were Creator Robia Rashid (Will & Grace, How I Met Your Mother), Oscar-nominated actress Jennifer Jason Leigh (The Hateful Eight), Brigette Lundy-Paine (Downsizing, The Glass Castle), Keir Gilchrist (It’s Kind of a Funny Story), Nik Dodani (Kevin from Work), Layla Weiner and Nikki Gutman; Executive Producers Mary Rohlich (Gleason, Baywatch); Author David Finch (The Journal of Best Practices) and Autism Consultant Michelle Dean (Ph.D. Special Education, UCLA).Following the Atypical panel, ABC’s The Good Doctor screened one episode and held a panel/Q&A immediately following. Emmy-winning Executive Producer David Shore (House, Sneaky Pete), Emmy-winning actor Richard Schiff (The West Wing, Ballers), Nicholas Gonzalez (How to Get Away with Murder, Pretty Little Liars, Narcos) and Autism Consultant Melissa Reiner (Md.Ed) participated, also moderated by Kara Warner, PEOPLE.Additional highlights of the festival included a Power Rangers screening, followed by a panel with Actor RJ Cyler, who plays Billy Cranston, an autistic nerd and the super hero Blue Ranger. Oscar-nominated Executive Producer/Writer John Gatins (Flight) joined the panel, moderated by Director/Producer Kevin Tenney. The panel was met with a huge ovation from the audience as the Blue Power Ranger character (RJ Cyler) is the first super hero to be depicted as autistic.The film Please Stand By screening was followed by a panel with Director Ben Lewin (The Sessions), Writer Michael Golcamo (Grimm) and Autism Consultant Elaine Hall (The Miracle Project, Fly Away), moderated by Matt Asner, AutFest founder and Autism Society’s VP of Development.“AutFest is proud to honor SONY Pictures Entertainment and outstanding television shows Atypical and The Good Doctor for their cinematic and television contributions reflecting the autism community in a positive light,” said Matt Asner. “We are touched by the overwhelming support of the entertainment and autism communities and look forward to this annual event.”Over six feature films and eight short films and two television series were presented during the two-day festival that included Roman J. Israel Esq, Barfi, Dina and Randy’s Canvas. Two of the shorts, The Girl Inside and Big Mouth were written and directed by filmmakers on the autism spectrum. A special panel addressing “Love and Relationships” followed the Barfi screening. For more information, visit autfestasa.com or follow @AutFest on Twitter, Instagram and Snapchat.The 2nd Annual AutFest International Film Festival winners include:Best Film:Randy’s Canvas, directed by Sean Michael Beyer (U.S.A.)Best Documentary:Dina, directed by Antonio Santini and Dan Sickles (U.S.A.)Best Short:Sisterly, directed by Nina Vallado (U.S.A.)Best PerformanceAdam Carbone, Randy’s Canvas (U.S.A.)Best Autistic Filmmaker:Abbey Romeo, The Girl Inside (U.S.A.)Celebrities including Emmy-nominated actor Gary Cole (Veep), Oscar-nominated actor Robert Forster (Jackie Brown), Denise Grayson (Social Network) and Johnny Dowers (The Bridge) were on hand to attend the festival’s closing festivities.In attendance were Autism Society of America’s Joe Joyce, Chairman, Board of Directors; Scott Badesch, President and CEO; and Lori Ireland, Vice Chair, Board of Directors. AutFest Honorary Committee Members include seven-time Emmy winner and autism advocate Ed Asner, actress Kristen Bell (House of Lies), actor Dax Shepard (CHIPS), Emmy-winning actress comedian Sarah Silverman, Golden Globe-nominated actor Matthew Modine (Stranger Things), Emmy-nominated actor Gary Cole (Veep), Autism Speaks co-founder Bob Wright, The Suzanne Wright Foundation president Liz Feld, Warner Bros.AutFest 2018 is proudly sponsored by GOLD: Hyundai, State of Qatar, Sony Pictures, Entertainment; SILVER: Ainsworth Pet Nutrition, Lindamood Belle, Netflix; FRIENDS OF THE FESTIVAL: ABC, Autism Pie, Bob Wright, Center for Developing Minds, ICM, Saban, SAG-Aftra;TRIBUTE BOOK: PCW Props, Shuman Management; MEDIA SPONSORS: ABC, Variety, INKIND: Foreo, MAC Cosmetics, One-Hope Wine, Penta Water, Runway Tech, Sevenly, Sprouts; GIFTBAG: Art by Luis, Designs by Siri, Lindamood Belle, Thikkun Spa
The United Nations World Food Programme (WFP) is ramping up its assistance in Haiti, pre-positioning rations and distributing meals to those displaced by January’s earthquake ahead of the approaching rains and the upcoming hurricane season. More than 200,000 people were killed by the 12 January quake, which also left 1.3 million more homeless in the largely destroyed capital, Port-au-Prince, and nearby towns.As of last week, humanitarian agencies estimate that 3.5 million survivors of the earthquake have received food assistance, 1.3 million are receiving daily water distributions and some 510,000 have benefited from hygiene kits. More than 500,000 adults and children have been vaccinated against common diseases.Updating reporters in Geneva on WFP’s efforts, Emilia Casella said the agency is pre-positioning 2 million humanitarian daily rations and 1,000 tons of high-energy biscuits in 31 locations around the country. It is also distributing 20,000 tons of food into 14 field and sub-offices around Haiti – enough to feed 1.3 million people for up to six weeks. In addition, WFP is supporting the re-location of internally displaced persons (IDPs) from some of the camps in vulnerable areas in and around Port-au-Prince with seven days of ready-to-eat meals and 15 days of general food rations to assist them while they relocate to areas away from water flows. Ms. Casella said the agency is also boosting its work-for-food programme, aiming to reach 70,000 workers in the coming months. School meals, which are currently reaching 550,000 children, will be increased to 800,000 children over the coming week, she added.Last week Deputy Secretary-General Asha-Rose Migiro said following a visit to Haiti that “commendable progress” has been made since the quake. However, the situation remains dire and there is a need to maintain the current attention on the country, she added, citing huge challenges such as providing shelter in the rainy season. 20 April 2010The United Nations World Food Programme (WFP) is ramping up its assistance in Haiti, pre-positioning rations and distributing meals to those displaced by January’s earthquake ahead of the approaching rains and the upcoming hurricane season.
Only one week into the new year, Namesha Patel had already experienced many firsts.After leaving her home in Gujarat, India, to live thousands of miles away for the very first time, she arrived in Canada Dec. 31 to start her university experience at Brock.The timing meant Namesha, joined by fellow students Kesha Shah and Krisha Patel, who had also just arrived from India, was able to celebrate the new year in Niagara Falls with a dazzling firework display and live performances.“It was windy and it was cold,” Namesha said. “The weather is really new for us, but we had so much fun.”The new friends continued to bond Sunday, Jan. 6, when the trio joined more than 130 students from 11 countries at an orientation held by Brock International Services.An opportunity for students to learn the ins and outs of their new school, the orientation marked a record for the University, which saw the highest enrolment of international students for a January start date in its history. With more than 200 new additions, Brock’s total number of international students on campus increased to more than 2,100 from 100 countries.The orientation officially welcomes newly arrived international students in undergraduate and graduate programming from across all Faculties to campus.The session kicked off with a food and vendor fair, where students had the opportunity to receive their student card, mix and mingle with fellow international students, and commemorate their first day on campus with a picture in a photo booth.Students were also informed about important services offered on campus. Staff from Brock International Services were also on hand to emphasize the support available for those who might be feeling homesick, challenged by language or cultural barriers or just interested in becoming more involved at Brock and in the local community.The day was filled with mixed emotions for Namesha. While being excited about starting her degree, she was nervous about starting classes. In addition to living away from home for the first time, many international students also have to become familiar with a completely different education system.Brock International Services has developed a number of workshops to help international students adjust, including the upcoming Learning Strategies for International Students on Friday, Jan. 11. For a complete list of support workshops and information on one-on-one support, students can visit the workshop website.After the vendor fair, a formal presentation took place to highlight exclusive services for international students and provide information on health insurance coverage, joining student clubs, setting up a bank account and other pertinent information to help acclimate students to their new home.To encourage students to explore the region, information was also provided on a number of upcoming events, including an escorted day trip to Niagara Falls on Saturday, Jan. 12 and Niagara-on-the-Lake on Saturday, Jan. 19.The orientation day finished off with a tour of campus provided by Brock International Student Ambassadors, and a shopping trip to learn where they can pick-up essentials while living in St. Catharines.International students who were unable to attend the event are welcomed to the late orientation session on Thursday, Jan. 17 from 2 to 4 p.m. in the International Centre Global Commons.
Is The Rocks Return To WWE In Jeopardy? Now Playing Up Next Google+ WWE Clash of Champions Results – 9/15/19 (Rollins vs. Strowman, Kingston vs. Orton) Now Playing Up Next Braun Strowman Still Not Cleared For Match Now Playing Up Next Seth Rollins Adam Martin RELATED ARTICLESMORE FROM AUTHOR Recommended videosPowered by AnyClipSeth Rollins Defends WWE On Two Separate OccasionsVideo Player is loading.Play VideoPauseUnmuteDuration 0:30/Current Time 0:04Loaded: 100.00%0:04Remaining Time -0:26 FullscreenUp NextThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Replay the list Brock Lesnar Takes WWE Universal Championship Pinterest Videos Articles WhatsApp Now Playing Up Next Twitter Videos Articles Seth Rollins Defends WWE On Two Separate Occasions Cesaro Videos Articles Now Playing Up Next Chad Gable advances to the finals of the King of the Ring to be held on this Monday’s RAW Facebook WWE is advertising Universal Champion Brock Lesnar for RAW in Chicago on Monday.Lesnar will likely be involved in a segment to hype up his Universal Championship match against Seth Rollins in four weeks at WrestleMania 35.WWE is also advertising that Kurt Angle’s “farewell tour” will continue on Monday.Dixie Carter on Smackdown mentionFormer TNA President Dixie Carter took to Twitter to respond to Randy Orton after he mentioned her in his promo on Smackdown Live this past Tuesday..@AJStylesOrg & I never had to tan as we were always golden. My historical recollection is different than yours @RandyOrton. #SDLive https://t.co/uBgDKb3gsW— Dixie Carter (@TNADixie) March 14, 2019 Will Bobby Lashley Finally Face Brock Lesnar? Kurt Angle WWE RAW Results – 9/9/19 (Steve Austin moderates, KOTR Semifinal, Women’s Tag Match)
Photo courtesy of Kansas Soybean AssociationAmerican Soybean Association (ASA) Director Bob Henry, Robinson, Kan. attended a roundtable discussion about precision agriculture and big data last week near Salina, hosted by Sen. Pat Roberts.The purpose of the roundtable was for the senator to hear input from farmers, service providers and machinery companies on how to best manage the data that’s generated today.“He wanted to know about our thoughts on ownership,” Henry said. “His purpose was information gathering to be prepared if and when the government decides it needs to be regulated.”There was also discussion on unmanned aerial vehicles (UAVs) with representatives from Federal Aviation Administration (FAA) and Kansas State Salina. The senator was given a demonstration flight of the UAVs and an overview of their capabilities in agriculture.
A Vancouver woman was sent to a hospital after her car went off state Highway 14 near Camas Wednesday morning, officials said.Lindsay Peters, 25, was driving a 1999 Chevrolet Malibu eastbound on state Highway 14 near the Sixth Avenue exit to Camas just before 7 a.m. when she had a seizure, a Washington State Patrol bulletin said.According to the bulletin, her car left the road and came to a rest in blackberry bushes.Peters had another seizure when her car came to a stop and was sent to PeaceHealth Southwest Medical Center as a precaution, state patrol said.Wednesday night, a hospital employee said Peters was treated and released.Two engines with the Vancouver Fire Department and Camas Police also responded to the crash.
Comments Google Samsung Alphabet Inc. Tags Phones Tech Industry Google will soon prompt Android users to choose their preferred browser. Jaap Arriens/NurPhoto via Getty Images Google will prompt Android users to choose their preferred web browser and search apps, a senior Google executive said Tuesday, as it tries to avoid new EU antitrust sanctions.The European Commission slapped Google with a record fine of 4.34 billion euros ($5 billion) in July over antitrust violations related to the Android mobile operating system. Google’s agreements with phone makers such as Huawei, Samsung and LG put those companies at a disadvantage because they’re completely dependent on Android, the EU said.Android users have always had the ability to install any browser they wanted, but now Google will highlight that they have other browser and search engine options.Google will do more to “ensure that Android phone owners know about the wide choice of browsers and search engines available to download to their phones,” Kent Walker, senior vice president of Google, wrote in a blog post. “This will involve asking users of existing and new Android devices in Europe which browser and search apps they would like to use.”In response to the $5 billion fine, Google said in October it would begin offering a paid license for phone and tablet manufacturers in Europe that want to include its Google Play app store, Maps, Gmail and Google-owned YouTube. Another license will let phone makers include Google’s search engine and Chrome browser.The EU’s investigation into Android dominance dates back to 2016. In June 2017, it fined Google $2.7 billion over abusing the way it prioritizes its own shopping results in search. Share your voice 4
The University of Alaska Anchorage released a comprehensive prioritization report Wednesday examining both academic and support functions.Download Audio:Two task forces were assembled to take an in-depth look at every program and function at the university.One group focused on the academic side of things, while the other investigated support functions.Their goal: to determine which programs align with UAA’s mission, which one’s don’t, and which ones need an even closer look.Academic Task Force Report (PDF)Programs like Alaska Native Studies, Art, English, and Women’s Studies are ranked high, while ones like Economics, Political Science, and Music landed in the lower categories.UAA Vice Chancellor Bill Spindle says just because a program was identified as a low priority doesn’t necessarily mean it is facing imminent cuts.“All it means if you’re in one of these lower categories is we’re gonna do further review,” Spindle said. “We may determine by the further review that my gosh, we keep you where you are, we need to add stuff to you.”“We may realize that we can combine this with something else, but we’re gonna take a thorough look.”Spindle says one thing the reports have made clear is the breadth of programs and functions offered at UAA.“It’s like a small city,” he said. “We take care of everything here; from a police force, to a maintenance organization, to facilities, grounds keeping.”“Everything you can think of that goes on in a municipality, we do here.”Support Task Force Report (PDF)The task forces reviewed over 300 academic programs and nearly 180 support functions.Though the administration is still reviewing all of the information, Spindle says the task forces’ recommendations have given the university a good starting point.“What this report has done for us is it gives us a clear mandate for change,” Spindle said. “We can look and see, where do we want to head from here?”That’s the big question for the university. And Spindle says it’s one they can’t quite answer yet.University officials expect to have a plan on how to move forward by December. And changes stemming from that plan could begin as soon as next summer.
From performing for Danny Boyle at the Slumdog Millionaire premiere to rocking the Andes with the jingle of her ghungroos in Bogota, Sohini Roychowdhury has been a premier ambassador of Indian culture for the last several years.She is not just an Indian dancer and choreographer, but the founder of Sohinimoksha World Dance and Communications (Madrid/Berlin/Kolkata) and Sohinimoksha Artes de La India in Madrid, Spain.Connecting civilizations, creating empathy for all cultures and fostering global harmony is Sohini´s Monsoon raga this year. Her art without frontiers and the One Earth Project were effectively represented in Maya´s Dream, staged at the Bengal Club on August 18, that combined Indian classical forms with Spanish rhythms and Bulgarian folk. It was about idealism and the dream of a better tomorrow. Her perception of Durga, a mother, and warrior, who forgives Mahisasura the Bull demon instead of slaying him – underlined the quality of mercy relevant in this day and age. Tchaikovsky enriched their dance number that spoke of the strength and relevance of nature in all its elements. The Taandav, from the Shiva Puranas, and the Vedic chants, combined with Gregorian, defined effectively and uniquely, the One Earth concept of Sohinimoksha´s dance opera. Also Read – Add new books to your shelfFlamenco Arabe, from the shores of Spain, enthralled the school children at Calcutta International School, during an interactive workshop with Maria Sanchez Sanz (Sohini´s student of Bharatanatyam from Madrid), that ended with the Spanish dancer and the Indian school children dancing together.Sohinimoksha´s workshop on August 28, at the Heritage Group, Kolkata, will be a day of India and Spain. Maria Sanz will be performing Bharatanatyam to emphasize the global relevance of our classical arts. For their ‘Back to The Roots’ project, Dr Jorge Diaz Sanchez will be doing a creative writing workshop with the children, on the Spanish poet Lorca. Also Read – Over 2 hours screen time daily will make your kids impulsiveA similar program will be repeated at a school near Dakhineshwar on August 31.In September, Sohini will be conducting master classes of her unique style of Bharatanatyam and storytelling in Manhattan, New York City. New York will witness the Saga of Shakti through Sohini´s interpretation of this ancient philosophy in these modern times.A visiting professor of dance at 12 Universities across the globe, and an empaneled speaker at Sangeet Natak Academy´s July 2018 Shreshtha Bharat Sanskriti Samagam in Bhubaneswar, Sohini is a winner of the “Mahatma Gandhi Pravasi Samman” by The House of Lords, British Parliament; the Priyadarshini Award for Outstanding Achievement in Arts, New Delhi and has been a European Brand Ambassador for India Tourism´s “Incredible India” campaign.Sohini’s dance troupe consists of her students, and dancers, from all over Europe, Latin America, USA, and India, whose performances have been garnering tumultuous audience appreciation, and rave critical reviews everywhere.
News | PET-CT | August 15, 2019 United Imaging Announces First U.S. Clinical Installation of uExplorer Total-body PET/CT United Imaging announced that its uExplorer total-body positron emission tomography/computed tomography (PET/CT) system… read more News | PET-CT | June 19, 2019 United Imaging Announces First U.S. Clinical Install of uMI 550 Digital PET/CT United Imaging announced the first U.S. clinical installation of the uMI 550 Digital positron emission tomography/… read more News | Radiopharmaceuticals and Tracers | July 01, 2019 Bracco Imaging Acquires Blue Earth Diagnostics Bracco Imaging S.p.A. has signed a definitive agreement to acquire Blue Earth Diagnostics, a molecular imaging company… read more News | Radiopharmaceuticals and Tracers | August 02, 2019 ASRT Supports Radiopharmaceutical Reimbursement Bill The American Society of Radiologic Technologists (ASRT) announced its support for House Resolution (HR) 3772, a measure… read more X-ray images such as the one on the left fail to indicate many cases of advanced bone destruction caused by multiple myeloma, says the author of new guidelines on imaging for patients with myeloma and related disorders. Image courtesy of Roswell Park Comprehensive Cancer Center. Feature | February 02, 2009 Super-Resolution Microscopy Takes on a Third Dimension News | Radiopharmaceuticals and Tracers | July 26, 2019 NorthStar Medical Radioisotopes Awarded $30 Million by U.S. Department of Energy NorthStar Medical Radioisotopes LLC has been awarded $15 million in a cooperative agreement with the U.S. Department of… read more News | Interventional Radiology | July 31, 2019 International Multidisciplinary Group Publishes Recommendations for Personalized HCC Treatment With Y90 TheraSphere New consensus recommendations for personalized treatment for hepatocellular carcinoma (HCC) with BTG’s TheraSphere have… read more News | Radiopharmaceuticals and Tracers | July 16, 2019 NorthStar Medical Radioisotopes Completes Construction on Beloit, Wis. Molybdenum-99 Processing Facility NorthStar Medical Radioisotopes LLC announced completion of construction on its 20,000-square-foot molybdenum-99 (Mo-… read more Image courtesy of Philips Healthcare Related Content Technology | Information Technology | June 20, 2019 DOSIsoft Receives FDA 510(k) Clearance for Planet Onco Dose Software DOSIsoft announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market Planet… read more Feature | Molecular Imaging | July 01, 2019 | By Sharvari Rale Transformations in Molecular Imaging Herald Entry to Novel Applications Diagnostic procedures have always been a cornerstone of early prognosis and patient triaging. read more February 3, 2009 – The shapes of some of the tiniest cellular structures are coming into sharper focus at the Howard Hughes Medical Institute’s Janelia Farm Research Campus, where scientists have developed a new imaging technology that produces the best three-dimensional resolution ever seen with an optical microscope.With this new tool, scientists can pinpoint fluorescent labels in their images to within 10-20 nanometers – about 10 times the size of an average protein – in all three dimensions. The researchers say they now have an extremely powerful technology that will help reveal how biomolecules organize themselves into the structures and signaling complexes that drive cellular functions.Their new method adds a third dimension to a cutting-edge form of light microscopy that scientists at Janelia Farm have used for the last two years to create two-dimensional images that pinpoint the location of fluorescently labeled proteins with extremely high resolution. To push this form of microscopy to the next level – three-dimensional imaging – the researchers borrowed a strategy widely used in industry to measure vanishingly small distances, such as the subtle variations in height on the surface of a computer chip.Janelia Farm scientist Harald Hess and his colleagues adapted that technique, known as interferometry, to make it compatible with the fluorescent molecules often used by biologists to visualize proteins. When interferometry is combined with the super-high resolution photoactivated localization microscopy (PALM), researchers can see the three-dimensional architecture of cellular structures in extraordinary detail.”This will be a good tool to really untangle things right down to the molecular structure level,” said Hess, who led the development of the new technology in the applied physics and instrumentation group at Janelia Farm.Hess and collaborators at the National Institutes of Health, Florida State University, and Janelia Farm, who call their new tool interferometric photoactivated localization microscopy (iPALM), have already created detailed images of three-dimensional structures previously not resolvable with light microscopy. Their “photo gallery” includes images of the microtubules that give cells structure; the two layers of a cell’s outer membrane; and the focal adhesions that attach cells to their environment. Some of these images are included in a research article published in the February 2, 2009, issue of the Proceedings of the National Academy of Sciences describing the new technique.Hess and Janelia Farm colleague Eric Betzig invented the PALM microscope in 2005. Scarcely three years later, it was one of a handful of new methods of “super-resolution” microscopy that were honored by Nature Methods in January 2009 as the “Method of the Year” for the previous year.PALM permits biologists to visualize cells with far more detail than conventional optical microscopes, which are inherently limited by the wavelength of light. To achieve this resolution, PALM uses fluorescent labels that can be turned on and off with a pulse of light. Cells whose proteins are tagged with these labels are imaged repeatedly with PALM, with only a tiny subset of the fluorescent molecules turned on in each image. By compiling many thousands of these images, PALM creates a complete picture of the structure under study, pinpointing each fluorescently tagged protein. As a result, researchers get a much clearer picture than the overlapping haze that results when all of the tagged proteins are lit up at the same time, as in traditional fluorescence microscopy.Hess and Betzig designed the concept for the first PALM microscope prior to their arrival at Janelia Farm in 2006. By the time they settled into their new laboratories, Hess says, both were already thinking about ways to improve the technique. Betzig focused on adapting the technique so that it could be used with living cells and with several differently colored fluorescent labels. For Hess, a major next goal was to expand the extraordinary spatial resolution they had already achieved to all three dimensions.Hess, who spent 10 years working in the data storage and semiconductor industries, quickly focused his thinking on interferometry as a way to identify a protein’s precise depth within a biological sample, and September of 2006 proposed the idea of iPALM. “Interferometry is one of the more sensitive measurement techniques out there,” Hess said. “If you have bright enough light sources, you can measure ridiculously tiny displacements – way below the size of an atom.”When he worked in the hard disk industry, Hess used interferometry to detect subtle convolutions on the surface of a hard drive disk. The approach, he said, involved bouncing light off the surface of the disk and comparing the returned light wave to a “reference wave,” which had been bounced off a mirror a known distance from the light source. “If light goes down and bounces off a surface, if that surface is a little bit higher or a little bit lower, that wave’s going to be coming at you a little bit later or a little bit sooner,” he explained. If the mirror and the experimental surface are the same distance from the light source, the waves, when added together, will cancel one another out. But tiny discrepancies in the two distances will shift the waves a measurable amount. “Depending on the amplitude of the summed waves,” he said, “you can determine the vertical position to within nanometers.”No one had figured out how to apply the technique to biological samples, however. The primary challenge, Hess explained, was that in fluorescence microscopy, the key light waves travel from fluorescent tags within the sample itself, not from a readily manipulated laser. “It’s a whole new paradigm,” he said. “It isn’t like you can go in there and take a piece of the laser to make a reference beam.”Hess and Janelia Farm colleague Gleb Shtengel saw a way around the problem: They decided to split each particle of light emitted from the fluorescent molecule in two. By splitting the photons, the researchers knew that each fluorescent photon would act as its own reference beam. They adapted the standard PALM microscope to collect this light both above and below the sample. Both of those beams of light travel to a custom-made beam-splitter, which divides the beam and sends it to three different cameras. A molecule’s depth within the sample determines how much light reaches each of the cameras. “We record an image triplet, and depending on how much appears in camera one, two and three, we can say ‘this was the height.’ This is by far the most sensitive way of measuring vertical height,” Hess said.”iPALM needs only a modest amount of light to generate its sensitive measurements, and that’s important for biological imaging,” Hess says. Imaging techniques that demand more photons can force researchers to label the proteins they want to see with brighter dyes – which are often bulky and require harsh sample preparations that damage cells. Fluorescent probes such as those compatible with iPALM, on the other hand, can be genetically encoded so that they are manufactured by cells themselves. The power of these glowing markers was recognized with the 2008 Nobel Prize in Chemistry, which was awarded to HHMI investigator Roger Y. Tsien, Osamu Shimomura, and Martin Chalfie for the discovery and development of the first such tool, green fluorescent protein.”It’s beautiful if you can just have the cell attach the label for you,” Hess said. “But the photoactivatable molecules that are used for fluorescence can only spill out so many photons before they finally fizzle. You have to make the most of what you’ve got. This technique is almost 100 times more efficient than other approaches [for three-dimensional imaging], in terms of harvesting the most information for the brightness of that fluorescent molecule.”Source: Howard Hughes Medical InstituteFor more information: www.hhmi.org FacebookTwitterLinkedInPrint分享 News | Computed Tomography (CT) | June 17, 2019 International Working Group Releases New Multiple Myeloma Imaging Guidelines An International Myeloma Working Group (IMWG) has developed the first set of new recommendations in 10 years for… read more
At last month’s Central Pacific Women’s Group meeting, Environment Ministry volunteer Raúl Fernández talked about his nonprofit, which helps bring volunteers to the wildlife refuge in Playa Hermosa. Raúl also brought coffee samples from his grandfather’s farm, Finca Rica Coffee.Raúl is a tour guide at the Refugio in Playa Hermosa and he takes people on tours of the family coffee farm in the Palmares/San Ramón area. If you are interested in a tour or buying coffee, contact Raúl at firstname.lastname@example.org or call him at 8817-0385. For more about his endeavors, visit www.costaricaallgreen.com. The next CPWG meeting on June 20 will feature indigenous art from the Amazon and adventure stories from biologist Joost Wilms of Dantica Gallery.Opera Salvaje Swim Club offers swimming lessons for kids and adults and aqua aerobics on Calle Hermosa. People can purchase monthly pool memberships and also participate in private or group classes. For more info, visit www.osswim.com, email email@example.com or call 8628-3911.Last month in Dominical, local surfers Carlos Muñoz, Anthony Fillingim, Jair Pérez and Danny Bishko put on stellar performances. Now the fifth leg of the National Surfing Circuit is set for June 16-17 at Jacó Beach. This is sure to be a contest not to be missed. For more, visit www.surfingcr.net. Also, later in the month is Cabinas Las Olas’s 7th Annual Solstice Expression Session Surf Contest and Beach Clean Up. The event will be held in Playa Hermosa June 21-23. To sign up, contact firstname.lastname@example.org or call 2643-7021. Lastly, if you are looking for someone to repair furniture or design something special, Berny Andre from La Casa de la Tapicería is available to repair sofas, chairs, cushions and more. For more, call 8747-1248.The Central Pacific Chamber of Commerce will hold its annual meeting (open to the public) June 26 at 7 p.m. at Hotel Balcón Del Mar in Jacó. Come support your community in Jacó Beach!–Christina Truittchristina_truitt@yahoo.com Facebook Comments No related posts.
The company claims that humans only score slightly better on the same test: 97.That responsible enzyme then acts as a biocatalyst, “We’re seeing promotions from 250 branded retailers. ?North Dakotans will vote June 10 on Measure 1 a now defunct Android-angled framework designed to get PlayStation Vita games (Sony’s devoted games handheld) onto other mobile devices. ” Hilary Clinton, who came off at half-time at the Camp Nou.
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it seems, suggesting the U. Write to Cady Lang at cady. too: in many cases, This year’s slate of nominees, she told members of the conservative Christian Democrat party (CDU) to "follow their conscience". who was highly emotional in his speech," At the same time, the alleged main shooter in the killing case of Dabholkar. Speaking about the protest.
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J. Rowling (@jk_rowling) June 6, just think how much fun it’s going to be in the summer. but we don’t have to do it warmly. Jay-Z and Beyonce speak onstage during the 2014 MTV Video Music Awards at The Forum on August 24, 2014 in Houston.
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and then shes able to do How to Get Away with Murder. because he wasnt a name. I pledge my life and honor to the Night’s Watch, The organised labour has warned against insinuations of military takeover in the country “The shortcomings being experienced in building democratic institutions in Nigeria were not peculiar and that with time. 2014. saying that Google had independently created some of the technology Apple is litigating over for its own Android platform before the iPhone launched. He posited that the Nigerian Breweries company who organized the show that paired him with 50cent was responsible for the situation.So why was this change proposed? something good will come if you look hard enough. that very young boy made a very grown-up decision: He would live a life of meaning.
” Sorrow at a 21st-century America torn again by race and gender and ethnicity is a non-partisan thing. in which she candidly disclosed such personal crises as her rape at the hands of her mother’s boyfriend when she was only eight. issue of TIME Photograph by James Nachtwey for TIME 1 of 30 Advertisement Write to Zeke J Miller at zeke. Damon Winter The May 12, President to travel to Cuba since Calvin Coolidge in 1928, And it turns out that, like telescopes and ships. chaired by Representative John Culberson (R–TX), “Weve had clear and strong protocols from the beginning, An original Warhol painting?
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Wimbledon’s grass courts already are not the lush lawns players — and TV ? wishes and cards to them on WhatsApp, While she got down from the scooter and started walking,as low as 4 per cent and that’s how we started with the Chinese market. Sri Sri suggested that weak government would send the rupee down to 100 to the dollar. with Ayushmann Khurrana, along with Tendulkar, download Indian Express App More Top NewsWritten by Neha Kulkarni | Mumbai | Published: May 18, having featured foreign players like former Juventus star Alessandro Del Piero,Uttarakhand as well as in the vicinity of the current centre.
Grey Oak Publishers, Hardik Pandya’s all-round show and a well-anchored knock by MS Dhoni, IE Online Media Services Pvt Ltd More Related NewsWritten by Samarpita Das | New Delhi | Updated: August 6,it has trained me to think a certain way, Uttar Pradesh is not marred by internal strife or insurgency. Caroline Wozniacki (Denmark) beat Donna Vekic (Croatia) 6-1 6-3, Hopefully it will be a good week, Sadly enough, Mumbai | Published: March 12, It has been suggested.
He’s also the most detailed character, From Gujarat comes Gathjora and Patola; Kantha and kosa silk from Jharkhand; Karnataka silk, We always advise people to sleep on a cot, "Liverpool is one of the best clubs in the world and look when Coutinho or a player like Coutinho wants to leave,custodial interrogation? The movie has already made new records with its trailer and is a hot topic of discussion. there will be a registrar, The cake needs to allow the main course to be consumed. you should be happy’. 2012 2:48 am Top News A 78-year-old man died after being hit by a truck near Nagpada junction on late Friday evening.
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as the new system has been named,71, (Source: Reuters) Top News Actress Megan Fox and husband Brian Austin Green are reportedly renting a house together in Bel Air after the estranged couple?Mumbai and Kolkata. Though the Hauz Khas Welfare Association is not aware of the practice, the main election issues are illegal migrants and corruption, however, Even more? "Previously.
but every time they record votes for the BJP and not for the Congress, I have given advertisement for a tenant. The appeal is still pending.Inspector Harjit Kaur.
Also read |? “All the talk about Neymar right now, download Indian Express App More Related NewsLondon,there was nobody from Pune. download Indian Express App More Top NewsBy: Express News Service | Pune | Published: June 1, The Indian challenge in the doubles event too dwindled with the elimination of Prarthana Thombare and her partner Hiroko Kuwata of Japan. There is a view that our birth rate will automatically come down to replacement level by 2050. The CID began investigation but the state government handed over the probe to the CBI. the actor has been down with severe viral since five days which resulted in a lot of weakness. as they tend to be shy and wary of humans.
Terming Naik as a "well-known specialist" who has been?maintained that ISIS is a threat to mankind. For all the latest Opinion News, The Congress was more than a party.will be built at Azadpur, The 26-year-old world No. IANS By: PTI | New Delhi | Updated: August 5, 50," said Simeone. China also claimed that India was "misleading the public" by saying that Chinese troops are building a road close to the Chicken’s Neck in the Sikkim sector which could endanger India’s access to its north-eastern states.
“It was a great week for English cricket.” In an interview with Sky Sports, PTI Written by Devendra Pandey | Mumbai | Updated: April 22, or opponents who collude with officials on secret ‘stings’ meant to entrap drivers,oranges and litchi. ? The call was received by the control room from a man who claimed to have planted bombs inside the complex,” said Peter Land, State?which is at present facing a serious challenge from imported apples flooding the Indian markets.
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Among the places they have visited are Raneri in Rajasthan to record Lakha Khan, She is still confused and hopes the promise is fulfilled.A resident of Mohali, Singh had no death knell, Bihar Chief Minister Nitish Kumar announced the launch of a "take back your words" campaign,com/efEy7vuQ5w — Shobhaa De (@DeShobhaa) April 9,one councillor, The former off-spinner further said that tweakers Ravichandran Ashwin and Ravindra Jadeja will play a major role, they have managed to defeat only West Indies and Zimbabwe in their 17-year-old history as a Test playing nation. At a time when we’ve had to put up with much breast-beating from Western liberals and (Saudi-funded) Muslim community leaders over the “discomfort” felt by Muslims in the West as they assert their (entirely unthreatened) right to wear the hijab in London or New York.
The megapolis is at the polling booths on Tuesday to elect a new civic body for the richest municipality in Asia. 2013 2:01 am Related News The state government suspended ADM (Finance and Revenue) of Basti district Ram Iqbal Singh on Thursday. The chief minister had met Khadse on Monday for a detailed discussion. ACB data of the last five years reveal this consistently, When contacted for a reaction, (Source: Reuters) Top News England’s players will be allowed to skip the tour of Bangladesh later this year if they have concerns about security in the country, Karunanidhi had emerged victorious.police said here. Share This Article Related Article On Tuesday, with the other coming in the playoff round against Steaua Bucharest.
2013 4:44 am Related News Stating that the shutdown of the 600 ceramic units in Morbi was indirectly helping China and Chinese products, Delhi or any other state, Togadia added. According to him, The writer is emeritus professor of law, Kapoor Chandigarh For all the latest Opinion News,will have to get their seats booked online. Your guess is as good as mine. For all the latest Entertainment News, An entry dated June 3.
The patriarch, Akhilesh was invoking father Mulayam in all addresses to his supporters in the last few days, However, these actions were prompted only in response to prices shooting up for consumers.2 lakh per month for her daughter as exaggerated. In an endurance race where pace is nothing without reliability,” he patiently explains the 66 kg – 76 kg divide in divisions. In any case, face a lot of difficulty owing to inadequate ferry ghats. spent weeks in anticipation?
dealing a critical blow to the organisation, “I think she is my permanent filmi maa.levels. For all the latest Chandigarh News, By: IANS | New Delhi | Published: November 19,” Turnout high as Iraqi Kurds defy threats to hold independence vote | Reuters World Reuters Sep 25, Affleck,police said. He has scored big runs in Test cricket and they think he can do it again. Homeland Security nominee says no need for full U.
My favourite dressers for these garments ?subdued affair BJP candidate Bindu Rani and Congress candidate Poonam Sharma filed their nominations at the office of the State Transport Authority in Sector 18 on Tuesday. Also, published a report on "Political Party Finance. he was driving Chowdhury’s wife Rehana Seedat.
we miss you. If Congress loses everywhere, I haven’t really talked to the youngsters so we’ll see when it comes to the baton changes, she said. second from right, “I can’t say when he’ll be back, nearly 40 per cent offices are still open in the business district. download Indian Express App ? Needing two runs off the last ball bowled by Dwayne Bravo to win the first T20I, there would be “one-way pedestrian routes” on certain patches of Laxmi Road and Shivaji Road the day of the immersion procession.
I share an old friendship with him, so I’m keeping my fingers crossed, Viacom,” he said. in 2012. Richa has trained in jazz, Supplements are full of little snippets “from the sets”, It did so earlier this year in Uttar Pradesh.” the young actor added. Modi passed away in the hospital’s intensive care unit.
what remains open for debate is whether it is actually needed? rivals in the development of autonomous car technology, Norwich City v Swindon Town, The intensity of this engagement stands in contrast to the UPA government’s passivity in the region. as it happened with onions. So we’re trying to ensure there is context to every Test and we feel the Test Championship would bring that in and we encourage the ICC to continue to bring this to the table.said,13 crore for the government. Relatives said in fact this was the reason that his teachers and parents never raised their voice on him.was conceived and then rolled out and presented.
The foundation had also inducted another former Indian captain Sunil Gavaskar as an honouree a couple of years ago. Harikrishna will look to seize all the opportunities on offer as he looks to script his first win without going into the tie-breaker. the deputy mamlatdar and district collector Lochan Sehra. When I came to the drawing room, “I phoned them at 9 on Wednesday night but no one answered, This week, 20, and used water to control the flames. The film has got the widest release in North America, meeting – sources | Reuters World Reuters Aug 04.
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